Dr. Jason Smith, University of Louisville Hospital's chief medical officer, said doctors who treated victims dealt with a "spectrum of injuries" consistent with an explosion, including blast injuries, thermal injuries and injuries from falling debris.

Residents across Louisville reported around 3 p.m. feeling the explosion, which occurred at Givaudan Sense Colour at 1901 Payne St.

The explosion occurred just east of downtown Louisville at 3:00 p.m., shattering windows of nearby homes and cutting power to the area.

“I went to the scene yesterday afternoon and saw all of our amazing first responders and partner agencies working hard, working together, risking their lives to ensure that the scene was safe," said Louisville Mayor Craig Greenberg. "That we rescued as many individuals as possible, so that everyone who was impacted was safe and would be protected.”

Kentucky’s governor says investigators will find out what caused a deadly explosion that ripped apart a Louisville factory

Former Vice President Mike Pence is urging GOP senators to reject President-elect Trump’s nomination of Robert F. Kennedy Jr. to lead the Department of Health and Human Services (HHS) because of his views on abortion.

Emergency management crews cleaned up damage Wednesday after a chemical plant explosion left two people dead and several others injured. The blast occurred Tuesday afternoon at the Givaudan Sense Colour facility in Louisville's Clifton neighborhood.